Mucosal Microbiome in Patients with Recurrent Aphthous Stomatitis

Role of mucosal injury in initiating recurrent aphthous stomatitis.

The buccal mucosa of 30 patients with recurrent aphthous stomatitis and 15 healthy controls was injured by suture and penetration with a tenaculum and a hypodermic needle and each of the six puncture wounds produced monitored for up to seven days for the development of ulcers. Altogether 26 lesions were induced in 13 patients, whereas none occurred in the controls (p less than 0.001). Sutures c...

Status of Neutrophils, Lymphocytes and Platelets in Patients with Recurrent Aphthous Stomatitis: A Retrospective Study

Introduction: The aim of this study was to evaluate the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and mean platelet volume (MPV) in patients with recurrent aphthous stomatitis (RAS).   Materials and Methods: Eighty patients who were diagnosed with RAS between January 2014 and January 2016 were included in this study. Eighty age- and gender-matched healthy subject...

Recurrent Aphthous Stomatitis

Recurrent aphthous stomatitis (RAS) is a common disorder affecting 5% to 66% of examined adult patient groups. There may be a female predominance in some adult and child patient groups.1–4 The ulceration usually commences in the second decade,5 although 40% of selected groups of children can have a history of RAS, ulceration beginning before 5 years of age, the frequency of affected patients ri...

Mucosal disease series. Number VI. Recurrent aphthous stomatitis.

Recurrent aphthous stomatitis (RAS; aphthae; canker sores) is a common condition which is characterized by multiple recurrent small, round or ovoid ulcers with circumscribed margins, erythematous haloes, and yellow or grey floors typically presenting first in childhood or adolescence. RAS occurs worldwide although it appears most common in the developed world. The aetiology of RAS is not entire...

Recurrent aphthous stomatitis.